报告主题：

Monitoring ATP in living cells and tissues - Using the fluorescent probe ATeam

报告人：

Ian Max Møller

Department of Molecular Biology and Genetics, Aarhus University, Denmark

报告时间：

10月18日（周三）16:00

报告地点：

农学院 A435

主持人：

舒庆尧 教授

报告人简介：

1981               Ph.D. in plant biochemistry at University of London, London, UK

2000-2001     Professor in Plant Physiology, Lund University

2001-2004     Professor in Plant Biochemistry, Risø National Laboratory

2005-2006     Professor in Plant Biochemistry, Royal Veterinary and Agricultural University, Copenhagen

2007-2009     Head of Department, Department of Genetics and Biotechnology, Aarhus University

2009-              Professor, Department of Molecular Biology and Genetics, Aarhus University

2010-2014     Visiting Professor at Chinese Academy of Sciences, Beijing

研究内容：

ATP is the energy currency of the cell. It is produced mainly in the mitochondria and the chloroplasts and it is used to power countless processes, such as membrane transport, biosynthesis, and regulation. I will here present a method based on the use of a fluorescent sensor ATeam to monitor the concentration of ATP inside living cells and tissues in real time. The method is extremely sensitive and gives us a detailed picture of how cellular metabolism responds to developmental and environmental clues.

De Col et al. (2017) ATP sensing in living plant cells reveals tissue gradients and stress dynamics of energy physiology. eLIFE 6:e26770. DOI: 10.7554/eLife.26770