报告题目：See Protein in Action Using Infrared Structural Biology
报告人：Aihua Xie
Department of Physics, Oklahoma State University, USA
主持人：华跃进教授
报告时间：2014年6月30日周一上午9:00
报告地点：紫金港校区农生环组团A座117室
Abstract：
Proteins are dynamic. Lack of technology to detect functionally important structural motions of proteins hinders our understanding of protein functions. Advancing technology often catalyzes new scientific discoveries and pushes the boundary of unknown. I will report an emerging technology: time-resolved infrared structural biology that has excellent time resolution and high structural sensitivity. Thus it is ideally suitable to probe the functionally important structural motions of proteins, including proton transfer, hydrogen-bond dynamics, and protein quakes. I will show that how time-resolved infrared structural biology is employed to study the “electrostatic epicenter” for protein quake and receptor activation in biological signaling using photoactive yellow protein.
