Title：
Monitoring ATP in living cells and tissues - Using the fluorescent probe ATeam
Lecturer：
Ian Max Møller
Department of Molecular Biology and Genetics, Aarhus University, Denmark
Time：
Oct. 18th，16:00
Venue:
A435, College of Agriculture and Biotechnology, Zijingang Campus
Biography：
1981 Ph.D. in plant biochemistry at University of London, London, UK
2000-2001 Professor in Plant Physiology, Lund University
2001-2004 Professor in Plant Biochemistry, Risø National Laboratory
2005-2006 Professor in Plant Biochemistry, Royal Veterinary and Agricultural University, Copenhagen
2007-2009 Head of Department, Department of Genetics and Biotechnology, Aarhus University
2009- Professor, Department of Molecular Biology and Genetics, Aarhus University
2010-2014 Visiting Professor at Chinese Academy of Sciences, Beijing
Research Areas：
ATP is the energy currency of the cell. It is produced mainly in the mitochondria and the chloroplasts and it is used to power countless processes, such as membrane transport, biosynthesis, and regulation. I will here present a method based on the use of a fluorescent sensor ATeam to monitor the concentration of ATP inside living cells and tissues in real time. The method is extremely sensitive and gives us a detailed picture of how cellular metabolism responds to developmental and environmental clues.
De Col et al. (2017) ATP sensing in living plant cells reveals tissue gradients and stress dynamics of energy physiology. eLIFE 6:e26770. DOI: 10.7554/eLife.26770