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CURRICULUM VITAE

SONG Fengming

  

Education

Ph.D, Zhejiang University, 2000, majored in Plant Pathology;

M.Sc, Zhejiang University, 1990, majored in Plant Pathology;

B.Sc, Zhejiang University, 1987, majored in Plant Protection.

  

Professional Experience

Professor, 2003.01-present, College of Agriculture and Biotechnology, Zhejiang University;

Associate professor, 1998-2002, College of Agriculture and Biotechnology, Zhejiang University;

Assistant professor, 1993-1997, College of Agriculture and Biotechnology, Zhejiang University;

Assistant, 1990-1993, College of Agriculture and Biotechnology, Zhejiang University;

Post-Doc research associate, 2005-2006, Department of Botany and Plant Pathology, Purdue University;

Visiting Scientist, 1998-2000, Department of Plant Pathology, University of Wisconsin at Madison.

  

Research areas

By combination of different approaches of biochemistry, molecular biology and functional genomics, we are focusing on: (1) molecular mechanism of disease resistance in rice, tomato and watermelon against fungal pathogens; (2) Isolation and identification of microbe-derived immune-inducing proteins and their potential application in crop disease control; and (3) Identification of key pathogenicity genes in Fusarium oxysporum f.sp. niveum and novel strategies for control of fungal diseases on watermelon and melon.

  

Ongoing projects

1. Functional analysis of rice MNAC1 and MNAC2 in disease resistance responses, National Key Research and Development Program of China, 2016-2020, Principle investigator;

2. Fungal diseases on watermelon and melon and their controls, China Agriculture Research System, 2010-2015, Principle investigator;

  

Publications

72. Iftikhar H, Naveed N, Virk N, Bhatti MF, Song F. 2017 In silico analysis reveals widespread presence of three gene families, MAPK, MAPKK and MAPKKK, of the MAPK cascade from crop plants of Solanaceae in comparison to the distantly-related syntenic species from Rubiaceae, coffee. PeerJ 5:e3255.

71. Hong Y, Yang Y, Zhang H, Huang L, Li D, Song F. 2017 Overexpression of MoSM1, encoding for an immunity-inducing protein from Magnaporthe oryzae, in rice confers broad-spectrum resistance against fungal and bacterial diseases. Scientific Reports, 7: 41037.

70. Ouyang Z, Liu S, Huang L, Hong Y, Li X, Huang L, Zhang Y, Zhang H, Li D, Song F. 2016 Tomato SlERF.A1, SlERF.B4, SlERF.C3 and SlERF.A3, members of B3 group of ERF family, are required for resistance to Botrytis cinerea. Frontiers in Plant Sciences, 7: 1964.

69. Zhou SM, Wang SH, Lin C, Song YZ, Zheng XX, Song F, Zhu CX. 2016 Molecular cloning and functional characterisation of the tomato E3 ubiquitin ligase SlBAH1 gene. Functional Plant Biology, 43: 1091–1101.

68. Huang L, Hong Y, Zhang H, Li D, Song F. 2016 Rice NAC transcription factor ONAC095 plays opposite roles in drought and cold stress tolerance. BMC Plant Biology, 16:203.

67. Dai Y, Cao Z, Huang L, Liu S, Shen Z, Wang Y, Wang H, Zhang H, Li D, Song F. 2016 CCR4-Not complex subunit Not2 plays critical roles in vegetative growth, conidiation and virulence in watermelon Fusarium wilt pathogen Fusarium oxysporum f. sp. niveum. Frontiers in Microbiology, 7:1449.

66. Zhang H, Hong Y, Huang L, Liu S, Tian L, Dai Y, Cao Z, Huang L, Li D, Song F. 2016 Virus-induced gene silencing-based functional analyses revealed the involvement of several putative trehalose-6-phosphate synthase/phosphatase genes in disease resistance against Botrytis cinerea and Pseudomonas syringae pv. tomato DC3000 in tomato. Frontiers in Plant Sciences, 7:1176.

65. Shen Q, Hu T, Bao M, Cao L, Zhang H, Song F, Xie Q, Zhou X. 2016 Tobacco RING E3 ligase NtRFP1 mediates ubiquitination and proteasomal degradation of a geminivirus-encoded βC1. Molecular Plant, 9(6): 911-25.

64. Zhang H, Hong Y, Huang L, Li D, Song F. 2016 Arabidopsis AtERF014 acts as a dual regulator that differentially modulates immunity against Pseudomonas syringae pv. tomato and Botrytis cinerea. Scientific Reports, 6: 30251.

63. Zhang H, Huang L, Hong Y, Song F. 2016 BOTRYTIS-INDUCED KINASE1, a plasma membrane-localized receptor-like protein kinase, is a negative regulator of phosphate homeostasis in Arabidopsis thaliana. BMC Plant Biology, 16(1): 152.

62. Hong Y, Zhang H, Huang L, Li D, Song F. 2016 Overexpression of a stress-responsive NAC transcription factor gene ONAC022 improves drought and salt tolerance in rice. Frontiers in Plant Sciences, 7: 4.

61. Song Q, Li D, Dai Y, Liu S, Huang L, Hong Y, Zhang H, Song F. 2015 Characterization, expression patterns and functional analysis of the MAPK and MAPKK genes in watermelon (Citrullus lanatus). BMC Plant Biology, 15(1):298.

60. Ouyang Z, Li X, Huang L, Hong Y, Zhang Y, Zhang H, Li D, Song F. 2015 Elicitin-like proteins Oli-D1 and Oli-D2 from Pythium oligandrum trigger hypersensitive response in Nicotiana benthamiana and induce resistance against Botrytis cinerea in tomato. Molecular Plant Pathology, 16(3):238-50.

59. Li D, Fu F, Zhang H, Song F. 2015 Genome-wide systematic characterization of the bZIP transcriptional factor family in tomato (Solanum lycopersicum L.). BMC Genomics, 16(1):771.

58. Li D, Zhang H, Song Q, Wang L, Liu S, Hong Y, Huang L, Song F. 2015 Tomato Sl3-MMP, a member of the Matrix metalloproteinase family, is required for disease resistance against Botrytis cinerea and Pseudomonas syringae pv. tomato DC3000. BMC Plant Biology, 15:143.

57. Zhang Y, Li D, Zhang H, Hong Y, Huang L, Liu S, Li X, Ouyang Z, Song F. 2015 Tomato histone H2B monoubiquitination enzymes SlHUB1 and SlHUB2 contribute to disease resistance against Botrytis cinerea through modulating the balance between SA- and JA/ET-mediated signaling pathways. BMC Plant Biology, 15(1):252.

56. Virk N, Li D, Tian L, Huang L, Hong Y, Li X, Zhang Y, Liu B, Zhang H, Song F. 2015 Arabidopsis Raf-like mitogen-activated protein kinase kinase kinase gene Raf43 is required for tolerance to multiple abiotic stresses. PLoS One, 10(7):e0133975.

55. Zhang H, Huang L, Dai Y, Liu S, Hong Y, Tian L, Huang L, Cao Z, Li D, Song F. 2015 Arabidopsis AtERF15 positively regulates immunity against Pseudomonas syringae pv. tomato DC3000 and Botrytis cinerea. Frontiers in Plant Sciences, 6:686.

54. Li X, Huang L, Hong Y, Zhang Y, Liu S, Li D, Zhang H, Song F. 2015 Co-silencing of tomato S-adenosylhomocysteine hydrolase genes confers increased immunity against Pseudomonas syringae pv. tomato. Frontiers in Plant Sciences, 6:717.

53. Li X, Zhang H, Tian L, Huang L, Liu S, Li D, Song F. 2015 Tomato SlRbohB, a member of the NADPH oxidase family, is required for disease resistance against Botrytis cinerea and tolerance to drought stress. Frontiers in Plant Sciences, 6:643.

52. Sun L, Huang L, Hong Y, Zhang H, Song F, Li D. 2015 Comprehensive analysis suggests overlapping expression of rice ONAC transcription factors in abiotic and biotic stress responses. International Journal of Molecular Sciences, 16: 4306-4326.

51. Huang L, Zhang H, Hong Y, Liu S, Li D, Song F. 2015 Stress-responsive expression, subcellular localization and protein–protein interactions of the rice metacaspase family. International Journal of Molecular Sciences, 16:16216-16241.

50. Zhang Y, Jin X, Ouyang Z, Li X, Liu B, Huang L, Hong Y, Zhang H, Song F, Li D. 2015 Vitamin B6 contributes to disease resistance against Pseudomonas syringae pv. tomato DC3000 and Botrytis cinerea in Arabidopsis thaliana. Journal of Plant Physiology, 75:21-25.

49. Zhang HJ, Jin XY, Huang L, Hong YB, Zhang YF, Ouyang ZG, Li XH, Song FM, Li DY. 2014 Molecular characterization of rice sphingosine-1-phosphate lyase gene OsSPL1 and functional analysis of its role in disease resistance response. Plant Cell Reports, 33:1745–1756.

48. Liu B, Hong Y, Zhang Y, Li X, Huang L, Zhang H, Li D, Song F. 2014 Tomato WRKY transcriptional factor SlDRW1 is required for disease resistance against Botrytis cinerea and tolerance to oxidative stress. Plant Science, 227:145-156.

47. Liu B, Ouyang Z, Zhang Y, Li X, Hong Y, Huang L, Liu S, Zhang H, Li D, Song F. 2014 Tomato NAC transcription factor SlSRN1 positively regulates defense response against biotic stress but negatively regulates abiotic stress response. PLoS One, 9(7):e102067.

46. Li X, Zhang Y, Huang L, Ouyang Z, Hong Y, Zhang H, Li D, Song F. 2014 Tomato SlMKK2 and SlMKK4 contribute to disease resistance against Botrytis cinerea. BMC Plant Biology, 14:166.

45. Li X, Huang L, Zhang Y, Ouyang Z, Hong Y, Zhang H, Li D, Song F. 2014 Tomato SR/CAMTA transcription factors SlSR1 and SlSR3L negatively regulate disease resistance response and SlSR1L positively modulates drought stress tolerance. BMC Plant Biology, 14:286.

44. Sun L, Feng Q, Yan Y, Pan Z, Li X, Song F, Yang H, Xu J, Bao N, Gu H. 2014 Paper-based electroanalytical devices for in situ determination of salicylic acid in living tomato leaves. Biosensors and Bioelectronics, 60:154-60.

43. Zhang Y, Liu B, Li X, Ouyang Z, Huang L, Hong Y, Zhang H, Li D, Song F. 2014 The de novo biosynthesis of vitamin B6 is required for disease resistance against Botrytis cinerea in tomato. Molecular Plant-Microbe Interactions, 27:688-99.

42. Li D, Zhang H, Hong Y, Huang L, Li X, Zhang Y, Ouyang Z, Song F. 2014 Genome-wide identification, biochemical characterization, and expression analyses of the YTH domain-containing RNA-binding protein family in Arabidopsis and rice. Plant Molecular Biology Reports,32:1169-1186.

41. Sun L, Zhang H, Li D, Huang L, Hong Y, Ding XS, Nelson RS, Zhou X, Song F. 2013 Functions of rice NAC transcriptional factors, ONAC122 and ONAC131, in defense responses against Magnaporthe grisea. Plant Molecular Biology, 81:4156.

40. Zhang H, Li L, Yu Y, Mo J, Sun L, Liu B, Li D, Song F. 2013 Cloning and characterization of two rice long-chain base kinase genes and their function in disease resistance and cell death. Molecular Biology Reports, 40:117127.

39. Li D, Wang F, Liu B, Zhang Y, Huang L, Zhang H, Song F. 2013 Ectopic expression of rice OsBIANK1, encoding an Ankyrin repeat-containing protein, in Arabidopsis confers enhanced disease resistance to Botrytis cinerea and Pseudomonas syringae. Journal of Phytopathology, 161:27–34.

38. Virk N, Liu B, Zhang H, Li X, Zhang Y, Li D, Song F. 2013 Tomato SlMPK4 is required for resistance against Botrytis cinerea and tolerance to drought stress. Acta Physiologiae Plantarum, 35:1211–1221.

37. Zhang H, Zhai J, Mo J, Li D, Song F. 2012 Overexpression of rice sphingosine-1-phoshpate lyase gene OsSPL1 in transgenic tobacco reduces salt and oxidative stress tolerance. Journal of Integrative Plant Biology, 54:652662.

36. Li W, Zhong S, Li G, Li Q, Mao B, Deng Y, Zhang H, Zeng L, Song F, He Z. 2011 Rice RING protein OsBBI1 with E3 ligase activity confers broad-spectrum resistance against Magnaporthe oryzae by modifying the cell wall defence. Cell Research, 21:835848.

35. Basnayake BM, Li D, Zhang H, Li G, Virk N, Song F. 2011 Arabidopsis DAL1 and DAL2, two RING finger proteins homologous to Drosophila DIAP1, are involved in regulation of programmed cell death. Plant Cell Reports, 30:3748.

34. Li G, Nasar V, Yang Y, Li W, Liu B, Sun L, Li D, Song F. 2011 Arabidopsis poly(ADP-ribose) glycohydrolase 1 is required for drought, osmotic and oxidative stress responses. Plant Science, 180:283291.

33. Shen Q, Liu Z, Song F, Xie Q, Hanley-Bowdoin L, Zhou X. 2011 Tomato SlSnRK1 protein interacts with and phosphorylates βC1, a pathogenesis protein encoded by a geminivirus β-satellite. Plant Physiology, 157(3):1394-1406.

32. Lu G, Guo S, Zhang H, Geng L, Song F, Fei Z, Xu Y. 2011 Transcriptional profiling of watermelon during its incompatible interaction with Fusarium oxysporum f. sp. niveum. European Journal of Plant Pathology, 131(4):585-601.

31. Zhang XC, Li DY, Zhang HJ, Wang XE, Zheng Z, Song F. 2010 Molecular characterization of rice OsBIANK1, encoding a plasma membrane-anchored ankyrin repeat protein, and its inducible expression in defense responses. Molecular Biology Reports, 37:653660.

30. Luo H, Laluk K, Lai Z, Veronese P, Song F, Mengiste T. 2010 The Arabidopsis Botrytis Susceptible1 Interactor defines a subclass of RING E3 ligases that regulate pathogen and stress responses. Plant Physiology, 154(4):1766-1782.

29. Fu L, Shi K, Gu M, Zhou Y, Dong D, Liang W, Song F, Yu J. 2010 Systemic induction and role of mitochondrial alternative oxidase and nitric oxide in a compatible tomato-Tobacco mosaic virus interaction. Molecular Plant-Microbe Interactions, 23(1):39-48.

28. Guo Y, Huang C, Xie Y, Song F, Zhou X. 2010 A tomato glutaredoxin gene SlGRX1 regulates plant responses to oxidative, drought and salt stresses. Planta, 232(6):1499-1509.

27. Yang Y, Zhang H, Li G, Li W, Wang X, Song F. 2009 Ectopic expression of MgSM1, a Cerato-platanin family protein from Magnaporthe grisea, confers broad-spectrum disease resistance in Arabidopsis. Plant Biotechnol Journal, 7:763-777.

26. Wang X, Basnayake BM, Zhang H, Li G, Li W, Virk N, Mengiste T, Song F. 2009 The Arabidopsis ATAF1, a NAC transcription factor, is a negative regulator of defense responses against necrotrophic fungal and bacterial pathogens. Molecular Plant-Microbe Interactions, 22:1227-1238.

25. Hu X, Zhang H, Li G, Yang Y, Zheng Z, Song F. 2009 Ectopic expression of a rice protein phosphatase 2C gene OsBIPP2C2 in tobacco improves disease resistance. Plant Cell Reporter, 28:985-995.

24. Zhang XC, Yu X, Zhang HJ, Song F. 2009 Molecular characterization of a defense-related AMP-binding protein gene, OsBIABP1, from rice. Journal of Zhejiang University SCIENCE B, 10:731-739.

23. Zhang HJ, Li GJ, Li W, Song F. 2009 Transgenic strategies for improving rice disease resistance. African Journal of Biotechnology, 8:1750-1757.

22. AbuQamar S, Chai MF, Luo H, Song F, Mengiste T. 2008 Tomato protein kinase 1b mediates signaling of plant responses to necrotrophic fungi and insect herbivory. The Plant Cell, 20:1964-1983.

21. Li D, Liu H, Zhang H, Wang X, Song F. 2008 OsBIRH1, a DEAD-box RNA helicase with functions in modulating defence responses against pathogen infection and oxidative stress. Journal of Experimental Botany, 59:2133-2146.

20. Liu H, Zhang H, Yang Y, Li G, Yang Y, Wang X, Basnayake BM, Li D, Song F. 2008 Functional analysis reveals pleiotropic effects of rice RING-H2 finger protein gene OsBIRF1 on regulation of growth and defense responses against abiotic and biotic stresses. Plant Molecular Biology, 68:17-30.

19. Liu H, Wang X, Zhang H, Yang Y, Ge X, Song F. 2008 A rice serine carboxypeptidase-like gene OsBISCPL1 is involved in regulation of defense responses against biotic and oxidative stress. Gene, 420:57-65.

18. Cao Y, Yang Y, Zhang H, Li D, Zheng Z, Song F. 2008 Overexpression of a rice defense-related F-box protein gene OsDRF1 in tobacco improves disease resistance through potentiation of defense gene expression. Physiologia Plantarum, 134:440-452.

17. Zhang W, Chen J, Zhang H, Song F. 2008 Overexpression of a rice diacylglycerol kinase gene OsBIDK1 enhances disease resistance in transgenic tobacco. Molecules and Cells, 26:258-264.

16. Song D, Song F, Zheng Z. 2008 OsBISERK1, a gene encoding a leucine-rich repeat receptor-like kinase, is differentially expressed during disease resistance responses in rice. Molecular Biology Reports, 35:275-283.

15. Chen J, Zhang W, Song F, Zheng Z. 2007 Phospholipase C/diacylglycerol kinase-mediated signalling is required for benzothiadiazole-induced oxidative burst and hypersensitive cell death in rice suspension-cultured cells. Protoplasma, 230:13-21.

14. Song D, Chen J, Song F, Zheng Z. 2006 A novel rice MAPK gene, OsBIMK2, is involved in disease resistance responses. Plant Biology, 8: 587-596.

13. CaoY, Song F, Goodman R, Zheng Z. 2006 Molecular characterization of four rice ethylene-responsive element binding protein genes and their expressions in response to biotic and abiotic stresses. Journal of Plant Physiology, 163: 1167-1178.

12. Cao Y, Wu Y, Zheng Z, Song F. 2006 Overexpression of the rice EREBP-like gene OsBIERF3 enhances disease resistance and salt tolerance in transgenic tobacco. Physiology and Molecular Plant pathology, 67: 202-211.

11. Zhu T, Song F, Zheng Z. 2006 Molecular characterization of the rice pathogenesis-related protein, OsPR-4b, and its antifungal activity against Rhizoctonia solani. Journal of Phytopathology, 154: 378-384.

10. Hu X, Song F, Zheng Z. 2006 Molecular characterization and expression analysis of a rice protein phosphatase 2C gene, OsBIPP2C1, and overexpression in transgenic tobacco conferred enhanced disease resistance and abiotic tolerance. Physiologia Plantarum, 127: 225-236.

9. Xu R, Song F, Zheng Z. 2006 OsBISAMT1, a gene encoding S-adenosyl -L-methionine:salicylic acid carboxyl methyltransferase, is differentially expressed in rice disease resistance responses. Molecular Biology Reports, 33:223-231.

8. Hu X, Song F, Zheng Z. 2006 Molecular cloning and expression analysis of rice OsTVLP1, encoding a protein with similarity to TGF-receptor interacting proteins and vacuolar assembly Vam6p/Vps39p proteins. DNA Sequence, 17:152-158.

7. Luo H, Song F, Goodman RM, Zheng Z. 2005 Up-regulation of OsBIHD1, a rice gene encoding BELL homeodomain transcriptional factor, in disease resistance responses. Plant Biology, 7: 459-468.

6. Luo H, Song F, Zheng Z. 2005 Overexpression in transgenic tobacco reveals different roles for the rice homeodomain gene OsBIHD1 in biotic and abiotic stress responses. Journal of Experimental Botany, 56: 2673-2682.

5. Song F, Goodman R. 2002 OsBIMK1, a novel MAP kinase gene from rice that is involved in disease resistance response. Planta, 215: 997-1005.

4. Song F, Goodman R. 2002 Cloning and identification of promoter of the tobacco Sar8.2b gene, a SAR gene involved in systemic acquired resistance. Gene, 290: 115-124.

3. Song F, Goodman R. 2002 Molecular cloning and characterization of a rice phosphoinositide-specific phospholipase C gene, OsPI-PLC1 that is activated in systemic acquired resistance. Physiological and Molecular Plant Pathology, 61: 31-40.

2. Song F, Goodman R. 2001 Molecular biology of disease resistance in rice. Physiological and Molecular Plant Pathology, 59:1-11.

1. Song FM, Goodman RM. 2001 Nitric oxide is dependent on, but is partially required for, salicylic acid in the signaling pathway in tobacco systemic acquired resistance. Molecular Plant-Microbe Interactions, 14:1458-1462.

  

  

Teaching

Undergraduates: Introduction to Plant Protection, Agricultural Plant Pathology;

Graduates: Molecular Plant Pathology, Molecular Farming.

  

Contact information

Email: fmsong@zju.edu.cn

Tel: 86-571-88982269