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鲍艳原 博士, 教授, 博士生导师

杭州市余杭塘路866号            
浙江大学昆虫科学研究所
邮编:310058
电话:0571-88982995
E-mail
yybao@zju.edu.cn 

鲍艳原

教育背景
1987.09-1991.07 内蒙古大学生物系动物学专业, 理学学士学位。
1998.09-1999.09 内蒙古大学生物系动物学专业研究生。
1999.10-2002.03 日本鸟取大学农学研究科生物资源科学专业, 农学硕士学位 。
2002.04-2005.03 日本鸟取大学联合农学研究科生物化学与生物技术专业, 农学博士学位。
 
工作经历
1991.09-1998.09 内蒙古自治区医药工业研究所助理工程师, 工程师。
2005.04-2006.04 日本理化学研究所免疫科学综合研究中心免疫机理研究室研究员。
2006.05-2016.12 浙江大学昆虫科学研究所副教授。                              
2016.01-2016.03 日本东京大学创成科学研究科特任准教授。                              
2016.12-至今    浙江大学昆虫科学研究所教授。
 
研究领域
主要从事昆虫免疫学、昆虫功能基因组等方面的研究工作。
 
教学工作
参与主讲的本科生课程:《环境生物学》(国家精品课程);
参与主讲的研究生课程:《昆虫生理生化学》、《昆虫生理学》、《昆虫分子科学》。


学术论文

 

  1. Yan-Yuan Bao* and Chuan-Xi Zhang (2018). Recent advances in molecular biology research of a rice pest, the brown planthopper. Journal of Integrative Agriculture Invited review paper.

  2. Hai-Jian Huang, Jia-Bao Lu, Qiao Li, Yan-Yuan Bao, Chuan-Xi Zhang (2018). Combined transcriptomic/proteomic analysis of salivary gland and secreted saliva in three planthopper species. Journal of Proteomics 172: 25-35.

  3. Le Xu, Hai-Jian Huang, Xiang Zhou, Cheng-Wen Liu, Yan-Yuan Bao* (2017). Pancreatic lipase-related protein 2 is essential for egg hatching in the brown planthopper, Nilaparvata lugens. Insect Molecular Biology 26(3), 277-285.

  4. Hai-Jian Huang, Cheng-Wen Liu, Xiang Zhou, Chuan-Xi Zhang, Yan-Yuan Bao* (2017). A mitochondrial membrane protein is a target for rice ragged stunt virus in its insect vector. Virus Research229:48-56.

  5. Jun-Jie Zhu, Feng Jiang, Xian-Hui Wang, Peng-Cheng Yang, Yan-Yuan Bao, Wan Zhao, Wei Wang, Hong Lu, Qian-Shuo Wang, Na Cui, Jing Li, Xiao-Fang Chen, Lan Luo, Jin-Ting Yu, Le Kang, Feng Cui (2017). Genome sequence of the small brown planthopper Laodelphax striatellus. GigaScience 6: 1-12

  6. Hai-Jian Huang, Cheng-Wen Liu, Hai-Jun Xu, Yan-Yuan Bao, Chuan-Xi Zhang (2017). Mucin-like protein, a saliva component involved in brown planthopper virulence and host adaptation. Journal of Insect Physiology 98: 223-230.

  7. Hai-Jian Huang, Cheng-Wen Liu, Xiao-Hui Huang, Xiang Zhou, Ji-Chong Zhuo, Chuan-Xi Zhang, Yan-Yuan Bao* (2016). Screening and functional analyses of Nilaparvata lugens salivary proteome.Journal of Proteome Research 15(6): 1883-1896.  

  8. Bing Yu, Dan-Ting Li, Si-Liang Wang, Hai-jun Xu, Yan-yuan Bao, Chuan-Xi Zhang 2016. Ion transport peptide regulates wing expansion and cuticle melanization in the brown planthopper, Nilaparvata lugens. Insect Molecular Biology25 (6): 778-787.

  9. Hai-Jian Huang, Yan-Yuan Bao*, Shu-Hua Lao, Xiao-Hui Huang, Yi-Zhou Ye, Jian-Xiang Wu, Hai-Jun Xu, Xue-Ping Zhou, Chuan-Xi Zhang (2015). Rice ragged stunt virus-induced apoptosis affects virus transmission from its insect vector, the brown planthopper to the rice plant. Scientific Reports 5:11413.

  10. Shu-Hua Lao, Xiao-Hui Huang, Hai-Jian Huang, Cheng-Wen Liu, Chuan-Xi Zhang, Yan-Yuan Bao* (2015). Genomic and transcriptomic insights into the cytochrome P450 monooxygenase gene repertoire in the rice pest brown planthopper, Nilaparvata lugens. Genomics 106: 301–309.

  11. Hai-Jun Xu, Jian Xue, Bo Lu, Xue-Chao Zhang, Ji-Chong Zhuo, Shu-Fang He, Xiao-Fang Ma, Ya-Qin Jiang, Hai-Wei Fan, Ji-Yu Xu, Yu-Xuan Ye, Peng-Lu Pan, Qiao Li, Yan-Yuan Bao, Fred Nijhout, Chuan-Xi Zhang (2015). Two insulin receptors determine alternative wing morphs in planthoppers. Nature doi:10.1038/nature14286.

  12. Hai-Jian Huang, Cheng-Wen Liu, Ye-Fang Cai, Min-Zhu Zhang, Yan-Yuan Bao,Chuan-Xi Zhang (2015). A salivary sheath protein essential for the interaction of the brown planthopper with rice plants. Insect Biochemistry and Molecular Biology 66: 77-87.

  13. Jian Xue, Xin Zhou, Chuan-Xi Zhang, Li-Li Yu, Hai-Wei Fan, Zhuo Wang, Hai-Jun Xu, Yu Xi, Zeng-Rong Zhu, Wen-Wu Zhou, Peng-Lu Pan, Bao-Ling Li, John K Colbourne, Hiroaki Noda, Yoshitaka Suetsugu, Tetsuya Kobayashi, Yuan Zheng, Shanlin Liu, Rui Zhang, Yang Liu, Ya-Dan Luo, Dong-Ming Fang, Yan Chen, Dong-Liang Zhan, Xiao-Dan Lv, Yue Cai, Zhao-Bao Wang, Hai-Jian Huang, Ruo-Lin Cheng, Xue-Chao Zhang, Yi-Han Lou, Bing Yu, Ji-Chong Zhuo, Yu-Xuan Ye, Wen-Qing Zhang, Zhi-Cheng Shen, Huan-Ming Yang, Jian Wang, Jun Wang, Yan-Yuan Bao*, Jia-An Cheng* (2014). Genomes of the rice pest brown planthopper and its endosymbionts reveal complex complementary contributions for host adaptation. Genome Biology 15:521.

  14. Yan-Yuan Bao, Xia Qin, Bing Yu, Li-Bo Chen, Zhe-Chao Wang, Chuan-Xi Zhang (2014). Genomic insights into the serine protease gene family and expression profile analysis in the planthopper, Nilaparvata lugens. BMC Genomics 15:507.

  15. Yan-Yuan BaoLv-Yu QuDong ZhaoLi-Bo Chen, Hong-Yuan JinLiang-Min XuXia Qin, Jia-An Cheng, Chuan-Xi Zhang (2013). The genome- and transcriptome-wide analysis of innate immunity in the brown planthopper, Nilaparvata lugens.BMC Genomics 14:160.

  16. Yan-Yuan Bao, Li-Bo Chen, Wen-Juan Wu, Dong Zhao, Ying Wang, Xia Qin, Chuan-Xi Zhang (2013). Direct interactions between bidensovirus BmDNV-Z proteins and midgut proteins from the virus target Bombyx mori. FEBS Journal 280: 939-949.

  17. Yan-Yuan Bao, Ying Wang, Wen-Juan Wu, Dong Zhao, Jian Xue, Bao-Qin Zhang, Zhi-Cheng Shen, Chuan-Xi Zhang (2012). De novo intestine-specific transcriptome of the brownplanthopper Nilaparvata lugens revealed potential functions in digestion, detoxification and immune response. Genomics 99(4): 256-264.

  18. Wen-Juan Wu, Ying Wang, Hai-Jian Huang, Yan-Yuan Bao*, Chuan-Xi Zhang (2012). Ecdysone receptor controls wing morphogenesis and melanization during rice planthopper metamorphosis. Journal of Insect Physiology 58(3): 420-426.

  19. Jian Xue, Nan Qiao, Wei Zhang, Ruo-Lin Cheng, Xiao-Qin Zhang, Yan-Yuan Bao, Yi-Peng Xu, Lin-Zhu Gu, Jing-Dong Jackie Han, Chuan-Xi Zhang (2012). Dynamic interactions between Bombyx mori nucleopolyhedrovirus and its host cells revealed by transcriptome analysis. Journal of Virology 86(13):7345-7359.

  20. Ying Wang, Hai-Wei Fan, Hai-Jian Huang, Wen-Juan Wu, Yan-Yuan Bao, Hai-Jun Xu, Zeng-Rong Zhu, Jia-An Cheng, Chuan-Xi Zhang (2012). Chitin synthase 1 gene and its two alternative splicing variants from two sap-sucking insects, Nilaparvata lugensand Laodelphax striatellus (Hemiptera: Delphacidae). Insect Biochemistry and Molecular Biology 42(9): 637-646.

  21. Bao-Ling Li, Wei Chen, Li Liu, Xue-Chao Zhang, Yan-Yuan Bao, Jia-An Cheng, Zeng-Rong Zhu, Chuan-Xi Zhang (2012). Molecular characterization of two acetylcholinesterase genes from the brown planthopper, Nilaparvata lugens (Hemiptera: Delphacidae). Pesticide Biochemistry and Physiology 102(3):198-203.

  22. Yan-Yuan Bao, Jian Xue, Wen-Juan Wu, Ying Wang, Zu-Yao Lv, Chuan-Xi Zhang (2011). An immune-induced Reeler protein is involved in the Bombyx mori melanization cascade. Insect Biochemistry and Molecular Biology 41(9): 696-706.

  23. Xiao-Feng Wang, Bao-Qin Zhang, Hai-Jun Xu, Ying-Jun Cui, Yi-Peng Xu, Min-Juan Zhang, Yeon Soo Han, Yong Seok Lee, Yan-Yuan Bao, Chuan-Xi Zhang (2011). ODV-associated Proteins of the Pieris rapae Granulovirus. Journal of Proteome Research 10(6): 2817-2827.

  24. Jun-Bo Luan, Jun-Min Li, Nélia Varela, Yong-Liang Wang, Fang-Fang Li, Yan-Yuan Bao, Chuan-Xi Zhang, Shu-Sheng Liu, Xiao-Wei Wang (2011).Global analysis of the transcriptional response of whitefly to Tomato Yellow Leaf Curl ChinaVirus reveals their relationship of Coevolved Adaptations. Journal of Virology85(7): 3330-3340.

  25. Jian Xue, Yan-Yuan Bao, Bao-ling Li, Yan-Bing Cheng, Zhi-Yu Peng, Hang Liu, Hai-Jun Xu, Zeng-Rong Zhu, Yong-Gen Lou, Jia-An Cheng, Chuan-Xi Zhang (2010). Transcriptome analysis of the brown planthopper Nilaparvata lugens. PLoS ONE 5(12): e14233.

  26. Yan-Yuan Bao, Bao-Ling Li, Zhao-Bu Liu, Jian Xue, Zeng-Rong Zhu, Jia-An Cheng, Chuan-Xi Zhang (2010). Triazophos up-regulated gene expression in the female brown planthopper, Nilaparvata lugens. Journal of Insect Physiology 56(9): 1087-1094.

  27. Xiao-Wei Wang, Jun-Bo Luan, Jun-Min Li, Yan-Yuan Bao, Chuan-Xi Zhang and Shu-Sheng Liu (2010). De novo characterization of a whitefly transcriptome and analysis of its gene expression during development. BMC Genomics 11: 400.

  28. Yan-Yuan Bao, Zu-Yao Lv, Zhao-Bu Liu, Jian Xue, Yi-Peng Xu, Chuan-Xi Zhang (2010). Comparative analysis of BmNPV responsive genes in fat body and haemocyte of Bombyx mori resistant and susceptible strains. Insect Molecular Biology 19(3): 347-358.

  29. Yi-Peng Xu, Zheng-Pei Ye, Chang-Ying Niu, Yan-Yuan Bao, Wen-BingWang, Wei-De Shen, Chuan-Xi Zhang(2010). Comparative analysis of the genomes of Bombyx mandarina and Bombyx mori nucleopolyhedroviruses. The Journal of Microbiology,48(1): 102-110.

  30. Yan-Yuan Bao, Xu-Dong Tang, Zu-Yao Lv, Xiu-Ye Wang, Cai-Hong Tian, Yi-Peng Xu, Chuan-Xi Zhang (2009). Gene expression profiling of resistant and susceptible Bombyx mori strains reveals nucleopolyhedrovirus-associated variations in host gene transcript levels. Genomics94(2), 138-145.

  31. Cai-Hong Tian, Jin-Fang Zhao, Yi-Peng Xu, Jian Xue, Bao-Qin Zhang, Ying-Jun Cui, Min-Juan Zhang, Yan-Yuan Bao, Chuan-Xi Zhang (2009).Involvement of Bombyx mori nucleopolyhedrovirus ORF41 (Bm41) in BV production and ODV envelopment.Virology387(1):184-192.

  32. Yan-Yuan Bao, Mu-Wang Li, Yun-Po Zhao, Jun-Qing Ge, Cheng-Shu Wang, Yong-Ping Huang, Chuan-Xi Zhang (2008). Differentially expressed genes in resistant and susceptible Bombyx mori strains infected with a densonucleosis virus. Insect Biochemistry and Molecular Biology38(9): 853-861.

  33. Hai-Jun Xu, Zhang-Nv Yang, Jin-Fang Zhao, Cai-Hong Tian, Jun-Qing Ge, Xu-Dong Tang,Yan-Yuan Bao, Chuan-Xi Zhang (2008). Bombyx mori nucleopolyhedrovirus ORF56 encodes an occlusion-derived virus protein and is not essential for budded virus production. Journal of General Virology89, 1212-1219.

  34. Atsushi Hijikata, Hiroshi Kitamura, Yayoi Kimura, Ryo Yokoyama, Yuichi Aiba, Yanyuan Bao, Shigeharu Fujita, Koji Hase, Shohei Hori, Yasuyuki Ishii, Osami Kanagawa, Hiroshi Kawamoto, Kazuya Kawano, Haruhiko Koseki, Masato Kubo, Ai Kurita-Miki, Tomohiro Kurosaki, Kyoko Masuda, Mitsumasa Nakata, Keisuke Oboki, Hiroshi Ohno, Mariko Okamoto, Yoshimichi Okayama, Jiyang O-Wang, Hirohisa Saito, Takashi Saito, Machie Sakuma, Katsuaki Sato, Kaori Sato, Ken-ichiro Seino, Ruka Setoguchi, Yuki Tamura, Masato Tanaka, Masaru Taniguchi, Ichiro Taniuchi, Annabelle Teng, Takeshi Watanabe, Hiroshi Watarai, Sho Yamasaki, Osamu Ohara* (2007). Construction of an open-access database that integrates cross-reference information from the transcriptome and proteome of immune cells. Bioinformatics. 23(21): 2934-2941.

  35. Yan-Yuan Bao, Yoshiaki Yamano, Isao Morishima (2007). β-1,3-Glucan inducible expression of prophenoloxidase-activating proteinase from eri-silkworm, Samia cynthia ricini. Comparative Biochemistry and Physiology Part B147, 45-48.

  36. Yan-Yuan Bao, Yoshiaki Yamano, Isao Morishima (2007). Induction of hemolin gene expression by bacterial cell wall components in eri-silkworm, Samia cynthia ricini. Comparative Biochemistry and Physiology Part B146,147-151.

  37. Kazuhiko Hashimoto, Keiko Mega, Yuji Matsumoto, Yan-Yuan Bao, Yoshiaki Yamano, Isao Morishima (2007). Three peptidoglycan recognition protein (PGRP) genes encoding potential amidase from eri-silkworm, Samia cynthia ricini. Comparative Biochemistry and Physiology Part B 148, 322-328.

  38. Xiu-Cui Ma, Zhang-Nv Yang, Jin-Yan Shang, Yan-Yuan Bao, Qiang Xiao, Chuan-Xi Zhang (2007). Genome sequence and organization of a nucleopolyhedrovirus that infects the tea looper caterpillar, Ectropis oblique. Virology360, 235-246.

  39. Yan-Yuan Bao, Yoshiaki Yamano, Isao Morishima (2005). A novel lebocin-like gene from eri-silkworm, Samia cynthia ricini, that does not encode the antibacterial peptide lebocin. Comparative Biochemistry and Physiology Part B 140, 127-131.

  40. Yan-Yuan Bao, Keiko Mega, Yoshiaki Yamano, Isao Morishima (2003). cDNA cloning and expression of bacteria-induced Hdd11 gene from eri-silkworm, Samia cynthia ricini. Comparative Biochemistry and Physiology Part C 136, 337-342.


国际交流与合作

承办国际交流活动
2016.03 承办第一届浙江大学-东京大学联合前沿生命科学研讨会(杭州)
2011.03 承办第一届浙江大学-日本静冈大学学生Workshop (杭州)
2012.03 承办第二届浙江大学-日本静冈大学学生Workshop (杭州)

参加国际学术会议

2017.11 第2届浙江大学-东京大学联合学术研讨会(日本,东京)

2016.11 22届国际动物学大会特邀报告(日本,冲绳)

2016.09 25届国际昆虫学大会(美国,奥兰多)

2012.08 24届国际昆虫学大会(韩国,大邱)

2010.11 国际水稻学会(越南,河内)

2008.03 亚太平洋蚕丝业及昆虫生物学技术大会(日本,名古屋)

2004.08 22届国际昆虫学大会 (澳大利亚,布利斯班)
2004.03
日本生物科学, 生物技术及农业化学学会2004年年度大会 (日本,广岛)
2003.10
日本生物化学学会 (日本,横滨)
2003.09
日本生物科学, 生物技术及农业化学学会西日本分会 (日本,鹿儿岛)

指导及协助指导研究生获奖情况

黄海剑 博士研究生 荣获国家奖学金 荣获2018年度浙江大学农学部优秀博士学位论文

劳淑华 硕士研究生 荣获国家奖学金

黄晓慧 硕士研究生 荣获国家奖学金

秦暇   硕士研究生 荣获国家奖学金

刘成稳 硕士研究生 荣获大北农奖学金

指导本科生赴海外高水平大学深造情况

金弘渊  赴日本东京大学攻读博士学位

叶祎舟  赴日本东京大学攻读硕士学位